The star has given the entirety of his £25,000 Mercury Prize prize money to the MVT, which operates to protect the Britain's small live music spots.
Fender was given the prize on 16 October as his new release People Watching was chosen as the best record of the previous year.
He has opted to hand the money over to the trust, in recognition of the essential function grassroots venues played in his early career.
"I personally wouldn't be doing my current career if it hadn't been for all the shows I performed around the region, and elsewhere, when I was starting out," remarked the artist. "These venues are renowned, but they are struggling."
From early 2023 onward, over 150 of these locations have permanently closed – approximately 16% of the whole industry in the UK.
In the last year, top acts including Pulp, Coldplay, Katy Perry and Sheeran have all backed the trust in its efforts to help venues survive, by applying a small levy to their ticket prices, which benefits independent venues.
He also participated, collecting more than £100,000 on his recent tour to help numerous local spots across the UK.
The donation assisted locations that were facing imminent closure due to issues stemming from flooding, fire incidents and personal losses, as well as permit problems, legal disputes and noise complaints.
Additional spaces received funding support in upgrading infrastructure and technical equipment that directly benefitted musicians and concertgoers.
"The notion that funds from concerts in large arenas supports the independent spots, where it begins for performers like me, is just common sense," Sam Fender has stated.
The musician is among several artists to give his honor winnings to good deeds.
In they received the prize in the year 1996 for their album Different Class, vocalist Jarvis Cocker stated that the act would contribute their cash to the non-profit the charity.
In 2002, artist she divided her bounty among several good causes, such as the NSPCC and a Sickle Cell organization.
"And I donated a thousand pounds to the center, to their classes, because I did gymnastics when I was younger and they required new equipment," the artist told the media.
Two years ago, they gave their prize money to the youth organization that nurtured their group, as well as other independent music bodies.
Also 1994 winners they contributed their prize to a multiple sclerosis charity after a close contact was diagnosed the disease.
"Receiving the award was quite enough," stated vocalist Heather Small. "The money was the cherry on top but we didn't require the cherry, because we had the main prize. So our victory touched another person's life."
Last week, the Music Venues Trust revealed it had saved a couple of small stages in the South East, by placing them under community ownership.
The Joiners in Southampton and the second in the city were purchased under the public acquisition program, which is backed by Arts Council England and supporters who buy "ownership units" in the venues.
